Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2504)
Related Products (2504)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Palitantin
0 ImagesCat. No.: HY-120154CAS No.: 15265-28-8Synonyms: (±)-PalitantinPalitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis.
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Pipercide
0 ImagesPipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide.
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FIKK9.1-IN-1
0 ImagesCat. No.: HY-156028CAS No.: 1448523-50-9FIKK9.1-IN-1 (Compound 1) is a FIKK9.1 inhibitor. FIKK9.1-IN-1 interacts with the ATP?binding residues in FIKK9.1. FIKK9.1-IN-1 is an antimalarial agent (IC50: 2.68 μg/mL) and disrupts the parasite life cycle and leads to the death of parasites.
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Antileishmanial agent-9
0 ImagesCat. No.: HY-147537CAS No.: 2477608-91-4Antileishmanial agent-9 (compound 16c) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. Antileishmanial agent-9 has relatively low cytotoxicity in L-6 cells (IC50 = 40.1 μM).
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Farnesyl acetate
0 ImagesCat. No.: HY-128430CAS No.: 29548-30-9Farnesyl acetate is a sesquiterpene isolated from the leaves of Amomum gagnepainii. Farnesyl acetate has significant toxicity against red palm weevil larvae with a LD50 of 7867 ppm.
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Dabequin phosphate
0 ImagesCat. No.: HY-122385CAS No.: 56548-51-7Dabequin phosphate is an antimalarial agent, that exhibits inhibitory activity against Plasmodium falciparum.
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Antimalarial agent 25
0 ImagesCat. No.: HY-149938CAS No.: 2944456-41-9Antimalarial agent 25 is an orally active 1,4-naphthoquinones derivative with antimalarial activity. Antimalarial agent 25 shows cytotoxicity against P. falciparum. Antimalarial agent 25 inhibits P. burghei induced parasitemia in vivo.
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D-Arabinopyranose-13C5
0 ImagesCat. No.: HY-N7082SPurity: 99.9%D-Arabinopyranos-13C5 is 13C labeled D-Arabinopyranos (HY-N7082). D-Arabinopyranose is a rare aldehyde pentose, and its ring-opened form is D-arabinose (HY-N0059). D-arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
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Veratraldehyde-13C
0 ImagesCat. No.: HY-W738270CAS No.: 1173022-44-0Synonyms: 3,4-Dimethoxy[7-13C]-benzaldehydeVeratraldehyde-13C (3,4-Dimethoxy[7-13C]-benzaldehyde) is the 13C-labeled Veratraldehyde (HY-N1096). Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent.
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Ethyl cinnamate (Standard)
0 ImagesEthyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta.
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Panowamycin A
0 ImagesCat. No.: HY-N16437CAS No.: 1375224-55-7Panowamycin A is an isochroman compound that can be produced by Streptomyces sp. K07-0010. Panowamycin A exhibits antitrypanosomal activity against the Trypanosoma brucei brucei GUTat 3.1 strain (IC50: 0.40 μg/mL). Panowamycin A shows weak cytotoxicity towards human fetal lung fibroblast MRC-5 cells (IC50: 2.95 μg/mL). Panowamycin A can be used for research in the field of antitrypanosomal studies.
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Clioxanide
0 ImagesCat. No.: HY-114969CAS No.: 14437-41-3Synonyms: NSC 233846; SYD 230; TremeradClioxanide is a potential anti-liver fluke (Fasciola hepatica) agent. The results showed that Clioxanide showed no efficacy against 4-week-old or 19-week-old flukes at doses of 135 mg/kg or 200 mg/kg. In contrast, hexachloroethane was very effective against older flukes, reaching 100% efficacy at lower doses. The study pointed out that laboratory mice may not be suitable for screening potential compounds against liver fluke infections in ruminants such as cattle and sheep. In addition, no obvious toxic reactions were observed in mice with Clioxanide.
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(-)-3-O-Acetylcatechin
0 ImagesCat. No.: HY-N18245CAS No.: 116935-88-7(-)-3-O-Acetylcatechin is a Leishmania amazonensis arginase inhibitor with an IC50 of 3.7 μM. (-)-3-O-Acetylcatechin can be used for the research of leishmaniasis.
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HDAC1-IN-3
0 ImagesCat. No.: HY-144297CAS No.: 2482998-35-4
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Clazuril
0 ImagesCat. No.: HY-101000CAS No.: 101831-36-1Synonyms: R62690Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle.
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Antileishmanial agent-20
0 ImagesCat. No.: HY-155549CAS No.: 3048504-67-9Antileishmanial agent-20 is selective towards Leishmania parasite. Antileishmanial agent-20 has IC50 value of 2.8 μM and 0.2 μM for L. infantum and L. braziliensis, respectively. Antileishmanial agent-20 can be used for parasites research.
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Aspyrone
0 ImagesCat. No.: HY-121003CAS No.: 17398-00-4Aspyrone is a polyketide fungal metabolite that has been found in Aspergillus and has diverse biological activities. It is active against a panel of 13 fungi when used at a concentration of 20 μg/mL and a panel of 21 bacteria in a disc assay when used at a concentration of 100 μg per disc.1 Aspyrone (10-1,000 mg/L) is nematocidal against P. penetrans.
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LASSBio-1736
0 ImagesCat. No.: HY-184205CAS No.: 1554691-37-0LASSBio-1736 is a Cysteine protease inhibitor and antimalarial agent. LASSBio-1736 targets the promastigote form of Leishmania major. LASSBio-1736 can be used in the research of leishmaniasis.
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Antileishmanial agent-30
0 ImagesCat. No.: HY-162833Antileishmanial agent-30 (compound 17k) is a potent inhibitor of leishmania, with the IC50, CC50, and SI of 0.2 μM, >100 μM and >500 for L. donovani.
